Fluorescence Lightsheet imaging solutions for photo-sensitve live samples and cleared organs / organoids

Light Sheet Systems

  • LifeCanvas SmartSPIM


    • Uniform axial resolution across entire sample
    • Rapid volumetric imaging
    • Custom-designed imaging chamber

  • Mizar Tilt


    • Designed to work with high and low NA objectives
    • Adapts to most inverted microscopes
    • Minimal-to-no photodamage or bleaching

  • L-SPI Large Selective Plane Illuminator


    • Live-cell imaging with ultra-low phototoxicity
    • Spatial and temporal fractionation of illumination
    • Orthogonal lightsheets reduce shadowing

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Tissue Preservation, Clearing & Labelling

  • LifeCanvas SmartBatch+


    • Multi-purpose tissue clearing system
    • 12 whole mouse brains in one day
    • time-efficient tissue processing

  • LifeCanvas SHIELD


    • Superior tissue preservation
    • Protects tissue for multi-round processing
    • Easy, fast & reliable

  • LifeCanvas EasyIndex


    • Perfect optical clearing
    • Compatible with many tissue types
    • Cost-effective and easy to use

  • LifeCanvas Clear+ Tissue Clearing


    • No tissue expansion or contraction
    • Preserves sample integrity and fluorescent proteins
    • Actively clears whole mouse brain in 1 day or passively clears in 1 week

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Single plane or lightsheet microscopy delivers “gentle” photon doses directly to the required focal plane and can significantly reduce phototoxicity and bleaching.  We offer our own unique solution for large (>1mm) samples designed to work with a new or existing upright micro or macroscope with air or water dipping lenses.
We are currently developing a related instrument for imaging small samples with high Numerical Aperture oil immersion lenses and are also suppliers and integrators of third-party solutions.