Photometrics Prime BSI

• 95% Quantum Efficiency
• 6.5µm x 6.5µm Pixel Area
• 1.6e- Read Noise

Product Description

High Resolution BSI Scientific CMOS

The Prime BSI Scientific CMOS camera delivers the perfect balance between high resolution imaging and sensitivity with an optimized pixel design and near perfect 95% Quantum Efficiency. This 4.2 Megapixel camera with 6.5µm pixels captures highly detailed images at high frame rates, making it the most versatile sCMOS for live cell imaging techniques, including Total Internal Reflection Fluorescence (TIRF), Ratiometric Imaging and Lightsheet microscopy.

4.2 Megapixel Camera
6.5µm x 6.5µm Pixel Area
95% Quantum Efficiency
Real-time Computational Capabilities

Download Data Sheet Manuals video support Get a Quote Comparisons Back to sCMOS Cameras

Additional information


• Sensor – Gpixel GSENSE2020BSI Scientific CMOS sensor
• Active Array Size – 2048 x 2048 (4.2 Megapixel)
• Pixel Area – 6.5μm x 6.5μm (42.25μm2)
• Sensor Area – 13.3mm x 13.3mm – 18.8mm diagonal
• Peak QE% – >95%
• Read Noise – 1.6e- (Median) – 1.8e- (RMS)
• Full-Well Capacity – 45,000e- (Combined Gain), 10,000e- (High Gain)
• Dynamic Range – 35,000:1 (Combined Gain)
• Bit Depth – 16-bit (Combined Gain), 11-bit (High Gain)
• Readout Mode – Rolling Shutter – Effective Global Shutter
• Binning – 2×2 (on FPGA)

Key Camera Features

• 95% Quantum Efficiency
• 6.5µm x 6.5µm Pixel Area
• 2048 x 2048 array – 4.2 Megapixel
• 1.6e- Read Noise
• 45,000e- Pixel Full Well
• 35,000:1 Dynamic Range
• 43.5fps @ 16-bit
• 63fps @ 11-bit

Primary Applications

• TIRF Microscopy
• Ratiometric Imaging
• Cell Motility
• Light Sheet Microscopy


Cooling Performance

Air Cooled
Liquid Cooled

Sensor Temperature

-20ºC @ 30ºC Ambient
-30ºC @ 30ºC Ambient

Dark Current



Digital Interface
Lens Interface
Mounting Points
Liquid Cooling

Camera Interface

PCIe, USB 3.0
2 x ¼ 20” mounting points per side to prevent rotation
Quick Disconnect Ports

Triggering Mode

Input Trigger Modes Trigger-First:


Output Trigger Modes Any Row:


Output Trigger Signals


Sequence triggered on first rising edge
Edge: Each frame triggered on rising edge
SMART Streaming: Fast iteration through multiple exposure times

Expose signal is high while any row is acquiring data
Rolling Shutter: Effective Global Shutter – Expose signal is high when all rows are acquiring data
Signal is High for set Exposure time – Readout Time

Expose Out (up to four signals), Read Out, Trigger Ready