Live-SR

• Maximum resolution up to 105nm*
• Acquisition speed up to 1000 fps
• Live / Focus mode for real time

Product Description

Live Super-Resolution Confocal Microscopy

The Live-SR is based on optically demodulated structured illumination technique with online processing. Combined with spinning confocal, it enables Super-Resolution to be achieved at high speed and low photo-toxicity, making it the ideal solution for live high resolution cell imaging. Moreover, because of the nature of the light modulation, no line or pattern artifact is created.

The Live-SR process can be run live during acquisition or integrated into an offline routine. Processing is parameter free making it very easy to use. Necessary data for processing are directly read from the acquisition software.

Contrast Images

Spinning Disk Confocal

Spinning Disk + Live-SR

Intensity profiles of a 100nm green fluorescent bead captured using a conventional spinning disk confocal microscope with or without the Live-SR system. FWHM were measured at 232.5nm and 123nm respectively.

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Additional information

Features

• Maximum resolution up to 105nm*
• Acquisition speed up to 1000 fps
• Live / Focus mode for real time
• Motorized bypass mode
• No specific fluorophors required
• Low photoxicity for live imaging
• Up to 6 channels
• Simultaneous multi-wavelength imaging (up to 4 channels)
• Compatible with any existing research microscope
• Compatible with CCD, EMCCD, SCMOS cameras
• No expertise required
• No structured artifact

Recent Publications

Myosin VI and Branched actin filaments mediate membrane constriction and fission of melanosomal tubule carriers – read here