Product Description
The ultimate active immunostaining device
Rapid immunostaining with unparalleled uniformity
Fast, easy and efficient
Label large, intact samples such as rodent organs an order of magnitude faster than with passive labeling (≤24 hours vs. weeks to months).
Turnkey operation – simply load the buffers and your sample & probes. Perform 2 distinct labeling experiments simultaneously thanks to SmartLabel’s dual chamber design.
Uses a small amount of antibody (as little as ~3 µg) to label tissues the size of a whole mouse brain.
Reliable
Prevents tissue damage with Stochastic Electrotransport technology (Kim, PNAS, 2015). Our nanoporous membranes (patent-pending) eliminate tissue contamination and probe loss.
Complete and Uniform Labeling
Achieves unparalleled uniformity of signal intensity from surface to core using LifeCanvas’s advanced eFLASH (Yun et al.. 2019) protocol.
Combines rapid, Stochastic Electrotransport-mediated (Kim et al., 2015) infiltration of probes into tissue with the SWITCH technique (Murray et al., 2015) of controlling probe binding kinetics.
Cost Savings by Avoiding Target Saturation
Prevents antibody depletion caused by excessive binding to superficial tissue sites and ensures the sample’s center is well-labeled.
Compatible with Many Cleared-Tissue Techniques
- SWITCH (Murray, Cell, 2015)
- MAP (Ku, Nature Biotechnology, 2016)
- SHIELD (Park, Nature Biotechnology, 2019)
Download Data Sheet Manual video support Get a Quote Back to Light Sheet Microscopy