Alvéole Primo 2

• Micropatterning
• Microfabrication
• Hydrogels

Product Description

Bioengineering unleashed

The Alveole Primo system provides micropatterning, hydrogel polymerization and microfabrication, all in a single device. It is designed to create bespoke in vitro cellular microenvironments and get better cell models for your cell biology experiments or cryo-ET studies.

PRIMO 2 is new generation hardware with compact footprint, new optical design allowing epi-fluorescence microscopy and faster performance.

Developed by Alvéole scientists after the LIMAP* technology (Strale P.O. et al, Adv Mater. 2016), the PRIMO maskless photopatterning system (DMD based) can engineer custom in vitro cell microenvironments through three techniques: micropatterning, hydrogel structuration and microfabrication.

 

PRIMO bioengineering technology

 

 

Developed by Alvéole scientists after the LIMAP* technology (Strale P.O. et al, Adv Mater. 2016), the PRIMO maskless photopatterning system (DMD based) can engineer custom in vitro cell microenvironments through three techniques: micropatterning, hydrogel structuration and microfabrication.

PRIMO workflow for better in vitro cell models:

  1. SUBSTRATE selection and preparation
  2. PATTERN DESIGN and upload in Leonardo software
  3. UV PROJECTION BY PRIMO for micropatterning, microfabrication, hydrogel polymerization
  4. USING CUSTOM in vitro CONDITIONS

 

Alvéole Primo 2 application note Manuals Get a Quote Back to advanced techniques

Additional information

Applications

• Micropatterning
PRIMO micropatterning system allows to fine-tune cell adhesion to mimic in vivo phenotypes, study cellular mechanisms or isolate cells in reproducible conditions for standardized assays.
• Microfabrication
PRIMO DMD-based photopatterning system can perform greyscale photolithography on greyscale resists to create complex 3D molds such as ramps, curving wells or microfluidic chips for organ-on-a-chip applications.
• Hydrogels
As a photopatterning system, PRIMO can also polymerize and photo-scission most commonly used hydrogels for 3D cell culture, spheroid formation or polymerizing permeable membranes in microfluidic chips.