Email a friend Print this page
Fura-2
Fura-2 Ratiometric Indicator
Ratiometric readout minimizes the effects of photobleaching, leakage, uneven loading, and varying cell thicknesses in mixed populations, delivering more robust and reproducible results Particularly well-suited for ratio-imaging microscopy Well-established in literature, with many citations in numerous cell lines.
Fura-2 is a ratiometric and sensitive indicator dye for measuring intracellular calcium. Since its introduction by Molecular Probes® in 1985, fura-2 has been cited in thousands of papers that describe its applications in a wide variety of cells. These important Ca2+ indicators, developed by Roger Tsien and collaborators, have made a major contribution to advances in the understanding of the role of calcium in cellular regulation. The ability to make ratio measurements with fura-2 is an important property of this probe.
(www.invitrogen.com)
Fura-2 imaging requires fast switching between wavelengths which can be provided by the following products:
