Products Header
Product Overview
The Optopatch patch clamp amplifier from Cairn Research is a general purpose amplifier, incorporating a number of unique features in order to optimise its performance across a wide range of applications. The amplifier is designed for patch clamp recording, with the unique addition of a lock-in amplifier to enable measurement of membrane capacitance and resistance. This built in device has a unique "track-in" mode that keeps the lock-in amplifier in perfect balance, maintaining discrimination between resistance and capacitance and providing linear calibrated resistance and capacitance outputs. The Optopatch includes several other unique features, including our patented optical technique for measuring small currents over a wide bandwidth (up to 200 KHz), and circuitry for protection against overcompensation of series resistance and electrode capacitance, safeguarding your cells during a recording.
Applications
  • Single channel recording
  • Whole cell recording
  • High resolution capacitance measurement
  • Fast, high impedance amplifier
  • Voltammetry
Features
  • Optical Headstage for high bandwidth and low noise
  • Differential reference input on headstage
  • True voltage follower in current clamp mode
  • Unique cell protection against overcompensation of series resistance and electrode capacitance
  • Calibrated resistance and capacitance outputs
  • Integral lock-in amplifier for membrane capacitance measurement
  • Choice of four or eight pole Bessel filtering
  • Gain and frequency telegraphing outputs
  • Electrode capacitance compensation of up to 15pF
  • Membrane capacitance compensation of up to 200pF with standard headstage
  • High resolution metering displays
  • Optional external control of many functions
More Information...
Hardware Options
The Optopatch is currently available with choice of either four or eight pole bessel filtering and can be supplied in isolation, or as part of a full data acquisition system.
Product Code Product Description
P600/BE4/000 Optopatch, patch clamp amplifier with 4 pole Bessel filter
P600/BE8/000 Optopatch, patch clamp amplifier with 8 pole Bessel filter
Headstage
Product Code Product Description
P605/STA/000 Optical Headstage (standard version)
P605/HIC/000 Optical Headstage, high capacitance version
P605/GOL/000 Optical Headstage, improved low noise “Gold” version
P606/UST/000 Optical Headstage Mount for Narishige UST-1
Software
Product Code Product Description
P555/INT/000 Cairn data interface unit
D-Strathclyde University of Strathclyde WCP patch clamp software (provided by Dr. John Dempster) (http://www.strath.ac.uk/Departments/PhysPharm/ses.htm)
D-PCI-MIO-16E-4 PCI acquistion card with 16 channel A/D ( 250KHz @ 12 bits resolution), 2 channel D/A & digital I/O (inc. 2m cable to Cairn Data Interface)
Additional Components
Additional components for a full electrophysiology system, such as anti-vibration tables, faraday cages and pipette micropositioners are also available. Please contact the Cairn Sales Department with details of your requirements.
Product Code Product Description
P610/000/000 Model Cell for the Optopatch
P630/A00/003 Adjustable shelf for all standard Faraday Cages
P630/FMS/533 Mesh Faraday Cage: Floor Standing: Standard height 7'; width 3'; depth 30”
P630/FMS/543 Mesh Faraday Cage: Floor Standing: Standard height 5'; width 4'; depth 30”
P630/FMS/733 Mesh Faraday Cage: Floor Standing: Extra height 7'; width 3'; depth 30”
P630/FMS/743 Mesh Faraday Cage: Floor Standing: Extra height 7'; width 4'; depth 30”
P630/FSS/533 Solid Panel Faraday Cage: Floor Standing: Standard Height 5'; width 3'; depth 30”
P630/FSS/543 Solid Panel Faraday Cage: Floor Standing: Standard Height 5'; width 4'; depth 30”
P630/FSS/733 Solid Panel Faraday Cage: Floor Standing: Extra Height 7'; width 3'; depth 30”
P630/FSS/743 Solid Panel Faraday Cage: Floor Standing: Extra Height 7'; width 4'; depth 30”
P635/T00/024 Tabletop Insturment Rack: Height: 24 inch